Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCytochrome P450 2C8(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent

LigandBDBM298468(US10125101, Example 18)Copy SMILESCopy InChI

Affinity DataIC50:  2.10E+4nMAssay Description:The inhibition of cytochrome P450 2C8-isoenzyme catalyzed deethylation of amodiaquine by the test compound is assayed at 37° C. with human liver micr...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetCytochrome P450 2C9(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent

LigandBDBM298468(US10125101, Example 18)Copy SMILESCopy InChI

Affinity DataIC50: >5.00E+4nMAssay Description:The inhibition of cytochrome P450 2C9-isoenzyme catalyzed hydroxylation of diclofenac by the test compound is assayed at 37° C. with human liver micr...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent

LigandBDBM298468(US10125101, Example 18)Copy SMILESCopy InChI

Affinity DataEC50:  5nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI