Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
BDBM298492(US10125101, Example 45 in WO 2013/178575)
BDBM298492(US10125101, Example 45 in WO 2013/178575)
BDBM298480(US10125101, Example 30)
IC50: 2.00E+4nMAssay Description:The inhibition of cytochrome P450 2C8-isoenzyme catalyzed deethylation of amodiaquine by the test compound is assayed at 37° C. with human liver micr...More data for this Ligand-Target Pair
BDBM298456((1S,2S)-2-(5-{(R)-4-[2,6-Dimethyl-4-(2-methyl-2H-t...)
IC50: 2.90E+4nMAssay Description:The inhibition of cytochrome P450 2C8-isoenzyme catalyzed deethylation of amodiaquine by the test compound is assayed at 37° C. with human liver micr...More data for this Ligand-Target Pair
BDBM298456((1S,2S)-2-(5-{(R)-4-[2,6-Dimethyl-4-(2-methyl-2H-t...)
IC50: >5.00E+4nMAssay Description:The inhibition of cytochrome P450 2C9-isoenzyme catalyzed hydroxylation of diclofenac by the test compound is assayed at 37° C. with human liver micr...More data for this Ligand-Target Pair
BDBM298480(US10125101, Example 30)
IC50: >5.00E+4nMAssay Description:The inhibition of cytochrome P450 2C9-isoenzyme catalyzed hydroxylation of diclofenac by the test compound is assayed at 37° C. with human liver micr...More data for this Ligand-Target Pair
BDBM298480(US10125101, Example 30)
BDBM298456((1S,2S)-2-(5-{(R)-4-[2,6-Dimethyl-4-(2-methyl-2H-t...)