Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 7 hits in this display
BDBM264460((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(1,5-dimeth...)
BDBM264459(6-(4-chlorophenyl)-3-cyclopropyl-5-(1,5-dimethyl-6...)
IC50: 49nMpH: 7.5Assay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM264459(6-(4-chlorophenyl)-3-cyclopropyl-5-(1,5-dimethyl-6...)
IC50: 52nMpH: 7.5Assay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM264460((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(1,5-dimeth...)
IC50: 73nMpH: 7.5Assay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM264460((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(1,5-dimeth...)
IC50: 74nMpH: 7.5Assay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM264460((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(1,5-dimeth...)
BDBM264459(6-(4-chlorophenyl)-3-cyclopropyl-5-(1,5-dimethyl-6...)
IC50: 3.30E+3nMpH: 7.5 T: 2°CAssay Description:In order to assess bromodomain selectivity, we set up a binding assay using the bromodomain encoded by the CREBBP gene. Compounds were tested in the ...More data for this Ligand-Target Pair