Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
BDBM380660(R-6-(4-chlorophenyl)-2-cyclopropyl-5-(1,5-dimethyl...)
BDBM380660(R-6-(4-chlorophenyl)-2-cyclopropyl-5-(1,5-dimethyl...)
IC50: 39nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380660(R-6-(4-chlorophenyl)-2-cyclopropyl-5-(1,5-dimethyl...)
IC50: 40nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380659(6-(4-chlorophenyl)-2-cyclopropyl-5-(1,5-dimethyl-6...)
IC50: 77nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380659(6-(4-chlorophenyl)-2-cyclopropyl-5-(1,5-dimethyl-6...)
IC50: 78nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380659(6-(4-chlorophenyl)-2-cyclopropyl-5-(1,5-dimethyl-6...)
IC50: 84nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380660(R-6-(4-chlorophenyl)-2-cyclopropyl-5-(1,5-dimethyl...)
BDBM380659(6-(4-chlorophenyl)-2-cyclopropyl-5-(1,5-dimethyl-6...)
IC50: 2.00E+3nMAssay Description:In order to assess bromodomain selectivity, we set up a binding assay using the bromodomain encoded by the CREBBP gene. Compounds were tested in the ...More data for this Ligand-Target Pair