Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL

LigandBDBM50352765(CHEMBL1823219)Copy SMILESCopy InChI

Affinity DataIC50:  11nMAssay Description:Inhibition of ALK activity by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL

LigandBDBM50352765(CHEMBL1823219)Copy SMILESCopy InChI

Affinity DataIC50:  50nMAssay Description:Inhibition of KIT activity by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL

LigandBDBM50352765(CHEMBL1823219)Copy SMILESCopy InChI

Affinity DataIC50:  61nMAssay Description:Inhibition of KDR activity by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL

LigandBDBM50352765(CHEMBL1823219)Copy SMILESCopy InChI

Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MET activity by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI