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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Catenin beta-1
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50436058
(CHEMBL254381 | PNU-74654 | US9738628, Compound PNU...)
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Affinity Data
Ki: 1.80E+3nM
Assay Description:
Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after...
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Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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Target
Catenin beta-1 [138-686]
(Homo sapiens (Human))
University of Utah Research Foundation
US Patent
Ligand
BDBM50436058
(CHEMBL254381 | PNU-74654 | US9738628, Compound PNU...)
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Affinity Data
Ki: 2.44E+4nM
Assay Description:
Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino...
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US Patent
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Target
Catenin beta-1 [138-686]
(Homo sapiens (Human))
University of Utah Research Foundation
US Patent
Ligand
BDBM50436058
(CHEMBL254381 | PNU-74654 | US9738628, Compound PNU...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.81E+5nM
Assay Description:
Experiments were performed in white opaque 384-well plates from PerkinElmer (Waltham, Mass.), and the samples were read on a Synergy 2 plate reader (...
More data for this Ligand-Target Pair
Target Info
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US Patent
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Target
Transcription factor 4
(Homo sapiens)
TBA
Ligand
BDBM50436058
(CHEMBL254381 | PNU-74654 | US9738628, Compound PNU...)
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Affinity Data
Kd: 450nM
Assay Description:
Affinity for CCK2 receptor assessed by inhibition of pentagastrin-stimulated acid secretion in perfused rat stomach
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Target Info
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Target
Transcription factor 4
(Homo sapiens)
TBA
Ligand
BDBM50436058
(CHEMBL254381 | PNU-74654 | US9738628, Compound PNU...)
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Copy InChI
Affinity Data
Kd: 450nM
Assay Description:
Inhibition of His6 tagged Tcf4 1-53/beta catenin (unknown origin) interaction by VP-ITC titration calorimeter method
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Target Info
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CHEMBL
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Target
Catenin beta-1
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50436058
(CHEMBL254381 | PNU-74654 | US9738628, Compound PNU...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 450nM
Assay Description:
Binding affinity to beta catenin ARD (134 to 671 residues) (unknown origin) assessed as dissociation constant
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Catenin beta-1
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50436058
(CHEMBL254381 | PNU-74654 | US9738628, Compound PNU...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 450nM
Assay Description:
Binding affinity to beta-catenin (134 to 671 residues) (unknown origin) expressed in Escherichia coli BL21 assessed as dissociation constant by isoth...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Catenin beta-1
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50436058
(CHEMBL254381 | PNU-74654 | US9738628, Compound PNU...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 450nM
Assay Description:
Inhibition of Tcf4 binding to beta-catenin (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI