Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 19 hits in this display
BDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
Ki: 148nMAssay Description:Inhibition of recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in sf9 cells using acetyl-Lys(Ac)-AMC as substrateMore data for this Ligand-Target Pair
BDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
BDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
IC50: 700nMAssay Description:HDAC inhibition assays can be performed, e.g., in a cell, in a cell extract, or in a cell-free mixture. Exemplary HDAC inhibition assays are describe...More data for this Ligand-Target Pair
BDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
BDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
IC50: 740nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
BDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
IC50: 2.00E+3nMAssay Description:HDAC inhibition assays can be performed, e.g., in a cell, in a cell extract, or in a cell-free mixture. Exemplary HDAC inhibition assays are describe...More data for this Ligand-Target Pair
BDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
IC50: 2.00E+3nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
BDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
IC50: 2.00E+3nMAssay Description:HDAC inhibition assays can be performed, e.g., in a cell, in a cell extract, or in a cell-free mixture. Exemplary HDAC inhibition assays are describe...More data for this Ligand-Target Pair
BDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
IC50: 3.05E+3nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
BDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
IC50: 3.73E+3nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
BDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
IC50: 3.73E+3nMAssay Description:HDAC inhibition assays can be performed, e.g., in a cell, in a cell extract, or in a cell-free mixture. Exemplary HDAC inhibition assays are describe...More data for this Ligand-Target Pair
BDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
IC50: 3.73E+3nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
BDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
IC50: 6.62E+4nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
BDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
IC50: >8.00E+4nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
BDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
IC50: >1.00E+5nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
BDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
IC50: >1.00E+5nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
BDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
IC50: >1.00E+5nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
BDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
IC50: >1.00E+5nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
BDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
IC50: >1.00E+5nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair