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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetHistone deacetylase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50564474(CHEMBL4795802)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant human HDAC2 using FLUOR-DE-LYS-Green as substrate incubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Beijing University Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50564474(CHEMBL4795802)
Affinity DataIC50:  71nMAssay Description:Inhibition of recombinant human HDAC1 using SIRT1 as substrate incubated for 10 mins followed by substrate addition and measured after 30 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50564474(CHEMBL4795802)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CDK2/CyclinA2 expressed in baculovirus infected Sf21 cells using histone H1 as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed