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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetHistone deacetylase 6(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50209835(CHEMBL3885496)
Affinity DataIC50:  66nMAssay Description:Inhibition of HDAC6 (unknown origin) after 20 hrs by SAMDI mass spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50209835(CHEMBL3885496)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant human COX2 using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition for 2 mins by Cayman...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50209835(CHEMBL3885496)
Affinity DataIC50:  412nMAssay Description:Inhibition of HDAC8 (unknown origin) after 2.5 hrs by SAMDI mass spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50209835(CHEMBL3885496)
Affinity DataIC50:  424nMAssay Description:Inhibition of HDAC3 (unknown origin) after 5 hrs by SAMDI mass spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50209835(CHEMBL3885496)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) after 24 hrs by SAMDI mass spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50209835(CHEMBL3885496)
Affinity DataIC50:  3.57E+3nMAssay Description:Inhibition of sheep COX1 using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition for 2 mins by Cayman based fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50209835(CHEMBL3885496)
Affinity DataIC50:  4.05E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) after 24 hrs by SAMDI mass spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed