Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 20 hits in this display
BDBM207629(US9265734, R01 | US9796664, Compound R01)
BDBM207629(US9265734, R01 | US9796664, Compound R01)
BDBM207629(US9265734, R01 | US9796664, Compound R01)
BDBM207629(US9265734, R01 | US9796664, Compound R01)
IC50: 60nMAssay Description:Inhibition of recombinant full length human HDAC3 expressed in insect Sf9 cells at 10 uM measured after 1 hr by EMSA analysisMore data for this Ligand-Target Pair
BDBM207629(US9265734, R01 | US9796664, Compound R01)
BDBM207629(US9265734, R01 | US9796664, Compound R01)
BDBM207629(US9265734, R01 | US9796664, Compound R01)
BDBM207629(US9265734, R01 | US9796664, Compound R01)
BDBM207629(US9265734, R01 | US9796664, Compound R01)
BDBM207629(US9265734, R01 | US9796664, Compound R01)
BDBM207629(US9265734, R01 | US9796664, Compound R01)
IC50: 1.98E+3nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
BDBM207629(US9265734, R01 | US9796664, Compound R01)
IC50: 1.98E+3nMAssay Description:HDAC inhibition assays can be performed, e.g., in a cell, in a cell extract, or in a cell-free mixture. Exemplary HDAC inhibition assays are describe...More data for this Ligand-Target Pair
BDBM207629(US9265734, R01 | US9796664, Compound R01)
IC50: 2.40E+3nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
BDBM207629(US9265734, R01 | US9796664, Compound R01)
IC50: 2.40E+3nMAssay Description:HDAC inhibition assays can be performed, e.g., in a cell, in a cell extract, or in a cell-free mixture. Exemplary HDAC inhibition assays are describe...More data for this Ligand-Target Pair
BDBM207629(US9265734, R01 | US9796664, Compound R01)
BDBM207629(US9265734, R01 | US9796664, Compound R01)
BDBM207629(US9265734, R01 | US9796664, Compound R01)
IC50: 1.07E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) preincubated for 2 hrs followed by Fluor-de-Lys substrate addition measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
BDBM207629(US9265734, R01 | US9796664, Compound R01)
BDBM207629(US9265734, R01 | US9796664, Compound R01)
BDBM207629(US9265734, R01 | US9796664, Compound R01)