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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
13
hits in this display
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50477395
(CHEMBL238520)
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Affinity Data
Ki: 0.398nM
Assay Description:
Displacement of [3H]WAY-100635 from human cloned 5HT1A receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50477395
(CHEMBL238520)
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Affinity Data
Ki: >1nM
Assay Description:
Agonist activity at rat 5HT1A receptor
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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GoogleScholar
Ligand Info
PC cid
PC sid
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Article
PubMed
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Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50477395
(CHEMBL238520)
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Affinity Data
Ki: 7.90nM
Assay Description:
Inhibition of [3H]5-HT uptake at SERT in rat cortical synaptosomes
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 7
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50477395
(CHEMBL238520)
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Affinity Data
Ki: 40nM
Assay Description:
Displacement of [3H]5CT from human cloned 5HT7a receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Ligand Info
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PC sid
In Depth
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Article
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Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50477395
(CHEMBL238520)
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Affinity Data
Ki: 251nM
Assay Description:
Displacement of [3H]5-HT from human cloned 5HT1D receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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antibodypedia
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Ligand Info
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PC sid
In Depth
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Article
PubMed
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Target
D(3) dopamine receptor
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50477395
(CHEMBL238520)
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Affinity Data
Ki: 501nM
Assay Description:
Displacement of [125I]iodosulpiride from human cloned D3 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
antibodypedia
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Ligand Info
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PC sid
In Depth
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Article
PubMed
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Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50477395
(CHEMBL238520)
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Affinity Data
Ki: 794nM
Assay Description:
Binding affinity at adrenergic beta 1 receptor
More data for this Ligand-Target Pair
Target Info
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KEGG
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antibodypedia
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Ligand Info
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In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50477395
(CHEMBL238520)
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Affinity Data
Ki: 1.00E+3nM
Assay Description:
Displacement of [3H]5-HT from human cloned 5HT1B receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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antibodypedia
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Ligand Info
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PC sid
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50477395
(CHEMBL238520)
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Affinity Data
Ki: 1.00E+3nM
Assay Description:
Displacement of [3H]5-HT from human cloned 5HT2B receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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antibodypedia
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Ligand Info
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PC sid
In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50477395
(CHEMBL238520)
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Affinity Data
Ki: <1.00E+3nM
Assay Description:
Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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antibodypedia
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Ligand Info
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PC sid
In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50477395
(CHEMBL238520)
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Affinity Data
Ki: 1.26E+3nM
Assay Description:
Displacement of [3H]mesulergine from human cloned 5HT2C receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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antibodypedia
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Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50477395
(CHEMBL238520)
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Affinity Data
Ki: 2.00E+3nM
Assay Description:
Displacement of [125I]iodosulpiride from human cloned D2 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50477395
(CHEMBL238520)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.00E+3nM
Assay Description:
Displacement of [3H]ketanserin from human cloned 5HT2A receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI