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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University of Porto

Curated by ChEMBL
LigandPNGBDBM23538(3-Carboxamide-coumarin deriv., 20 | 6-methyl-2-oxo...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23538(3-Carboxamide-coumarin deriv., 20 | 6-methyl-2-oxo...)
Affinity DataIC50:  2.30E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23538(3-Carboxamide-coumarin deriv., 20 | 6-methyl-2-oxo...)
Affinity DataIC50: >5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23538(3-Carboxamide-coumarin deriv., 20 | 6-methyl-2-oxo...)
Affinity DataIC50: >5.00E+4nMAssay Description: After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23538(3-Carboxamide-coumarin deriv., 20 | 6-methyl-2-oxo...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23538(3-Carboxamide-coumarin deriv., 20 | 6-methyl-2-oxo...)
Affinity DataAssay Description: After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed