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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
18
hits in this display
Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50084141
((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
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Affinity Data
Ki: 290nM
Assay Description:
Agonist potency against cloned metabotropic glutamate receptor 5
More data for this Ligand-Target Pair
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Target
Metabotropic glutamate receptor 4
(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50084141
((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
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Affinity Data
Ki: 2.60E+4nM
Assay Description:
Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)
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Target
Metabotropic glutamate receptor 1
(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50084141
((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
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Affinity Data
Ki: >1.00E+5nM
Assay Description:
Agonist potency against cloned human metabotropic glutamate receptor 1
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Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50084141
((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
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Affinity Data
Ki: >1.00E+5nM
Assay Description:
Antagonist potency against cloned Metabotropic glutamate receptor 2
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Target
Metabotropic glutamate receptor 8
(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50084141
((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
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Affinity Data
Ki: >1.00E+5nM
Assay Description:
Agonist potency against cloned Metabotropic glutamate receptor 8 (mGluR-8).
More data for this Ligand-Target Pair
Target Info
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Target
Metabotropic glutamate receptor 3
(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50084141
((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
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Affinity Data
Ki: >1.00E+5nM
Assay Description:
Agonist potency against cloned Metabotropic glutamate receptor 3 (mGluR-3).
More data for this Ligand-Target Pair
Target Info
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Target
Metabotropic glutamate receptor 7
(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50084141
((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
Copy SMILES
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Affinity Data
Ki: >1.00E+5nM
Assay Description:
Agonist potency against cloned Metabotropic glutamate receptor 7 (mGluR-7).
More data for this Ligand-Target Pair
Target Info
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Target
Metabotropic glutamate receptor 6
(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50084141
((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
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Affinity Data
Ki: >1.00E+5nM
Assay Description:
Agonist potency against cloned Metabotropic glutamate receptor 6 (mGluR-6).
More data for this Ligand-Target Pair
Target Info
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Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50084141
((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
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Affinity Data
IC50: 290nM
Assay Description:
Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5)
More data for this Ligand-Target Pair
Target Info
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Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by
ChEMBL
Ligand
BDBM50084141
((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
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Affinity Data
IC50: 1.08E+3nM
Assay Description:
Inhibition of [3H]MPEP binding to mGluR5 in rat brain membrane
More data for this Ligand-Target Pair
Target Info
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Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50084141
((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.10E+3nM
Assay Description:
Tested in vitro binding affinity for displacement of [3H]-M-MPEP from membrane of L(-tk) cells expressing the Metabotropic glutamate receptor 5, acti...
More data for this Ligand-Target Pair
Target Info
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Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50084141
((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.00E+3nM
Assay Description:
In vitro for inhibitory activity of compound against recombinant Metabotropic glutamate receptor 5 evaluated as inhibition of quisqualate-stimulated ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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CHEMBL
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Article
PubMed
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Target
Luciferin 4-monooxygenase
(Photinus pyralis)
National Human Genome Research Institute
Curated by
ChEMBL
Ligand
BDBM50084141
((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
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Affinity Data
IC50: 4.30E+3nM
Assay Description:
Inhibition of Photinus pyralis luciferase
More data for this Ligand-Target Pair
Target Info
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Target
Luciferin 4-monooxygenase
(Photinus pyralis)
National Human Genome Research Institute
Curated by
ChEMBL
Ligand
BDBM50084141
((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
Copy SMILES
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Affinity Data
IC50: 1.10E+4nM
Assay Description:
Inhibition of Photinus pyralis luciferase by Easy lite assay
More data for this Ligand-Target Pair
Target Info
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Target
Luciferin 4-monooxygenase
(Photinus pyralis)
National Human Genome Research Institute
Curated by
ChEMBL
Ligand
BDBM50084141
((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.70E+4nM
Assay Description:
Inhibition of Photinus pyralis luciferase by PK-Light assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Luciferin 4-monooxygenase
(Photinus pyralis)
National Human Genome Research Institute
Curated by
ChEMBL
Ligand
BDBM50084141
((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.40E+4nM
Assay Description:
Inhibition of Photinus pyralis luciferase by BrightGlo reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Luciferin 4-monooxygenase
(Photinus pyralis)
National Human Genome Research Institute
Curated by
ChEMBL
Ligand
BDBM50084141
((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of Photinus pyralis luciferase by Steady-Glo reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 1
(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50084141
((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Compound was tested for its agonist activity against Ser165 and Thr188 (Metabotropic glutamate receptor 1) receptor.
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
antibodypedia
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CHEMBL
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PC sid
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Copy BDB DOI