Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))TBA

LigandBDBM50409937(CHEMBL184770)Copy SMILESCopy InChI

Affinity DataKi:  5.10nMAssay Description:Binding affinity to 5-HT2A receptor (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

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Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA

LigandBDBM50409937(CHEMBL184770)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Binding affinity to 5-HT2C receptor (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

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TargetD(2) dopamine receptor(Homo sapiens (Human))TBA

LigandBDBM50409937(CHEMBL184770)Copy SMILESCopy InChI

Affinity DataKi:  51nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))TBA

LigandBDBM50409937(CHEMBL184770)Copy SMILESCopy InChI

Affinity DataKi:  83nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

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TargetD(1A) dopamine receptor(Homo sapiens (Human))TBA

LigandBDBM50409937(CHEMBL184770)Copy SMILESCopy InChI

Affinity DataKi:  4.68E+3nMAssay Description:Binding affinity to dopamine D1 receptor (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

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Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))TBA

LigandBDBM50409937(CHEMBL184770)Copy SMILESCopy InChI

Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5-HT3 receptor (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

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TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Institute For Biological Research

Curated by ChEMBL

LigandBDBM50409937(CHEMBL184770)Copy SMILESCopy InChI

Affinity DataIC50:  260nMAssay Description:Inhibitory concentration against reuptake of 5-HT from rat synaptosomesMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

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TargetSodium-dependent serotonin transporter(Homo sapiens (Human))TBA

LigandBDBM50409937(CHEMBL184770)Copy SMILESCopy InChI

Affinity DataIC50:  260nMAssay Description:Inhibition of 5-HT uptake at SERT (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
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