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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Eberhard Karls University Tuebingen
Curated by
ChEMBL
Ligand
BDBM50297890
(2-(4-(3-(2,3-dimethylphenoxy)propoxy)phenylthio)ac...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of 5-lipoxygenase in A23187-stimulated human PMNL assessed as enzyme product formation preincubated 15 mins by RP-HPLC analysis in presenc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Eberhard Karls University Tuebingen
Curated by
ChEMBL
Ligand
BDBM50297890
(2-(4-(3-(2,3-dimethylphenoxy)propoxy)phenylthio)ac...)
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Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant 5-lipoxygenase expressed in Escherichia coli BL21 assessed as enzyme product formation using using arachidonic acid a...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin E synthase
(Homo sapiens (Human))
Eberhard Karls University Tuebingen
Curated by
ChEMBL
Ligand
BDBM50297890
(2-(4-(3-(2,3-dimethylphenoxy)propoxy)phenylthio)ac...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as reduction of PGE2 formation from PGH2 after 15 mins
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Goethe-University Frankfurt
Curated by
ChEMBL
Ligand
BDBM50297890
(2-(4-(3-(2,3-dimethylphenoxy)propoxy)phenylthio)ac...)
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Affinity Data
EC50: 3.80E+3nM
Assay Description:
Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
Goethe-University Frankfurt
Curated by
ChEMBL
Ligand
BDBM50297890
(2-(4-(3-(2,3-dimethylphenoxy)propoxy)phenylthio)ac...)
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Affinity Data
EC50: 600nM
Assay Description:
Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human))
Goethe-University Frankfurt
Curated by
ChEMBL
Ligand
BDBM50297890
(2-(4-(3-(2,3-dimethylphenoxy)propoxy)phenylthio)ac...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.40E+3nM
Assay Description:
Agonist activity at human PPARbeta expressed in african green monkey COS7 cells by Gal4 transactivation assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI