Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCathepsin D(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50172103(CHEMBL3808672)Copy SMILESCopy InChI

Affinity DataIC50:  510nMAssay Description:Inhibition of Cathepsin D (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50172103(CHEMBL3808672)Copy SMILESCopy InChI

Affinity DataKd:  140nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI