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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
University Of Southern Denmark
Curated by
ChEMBL
Ligand
BDBM50275597
(3-(4-(o-Tolylethynyl)phenyl)propanoic acid | CHEMB...)
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Affinity Data
Ki: 631nM
Assay Description:
Displacement of 3-(2-Fluoro-4-((2'-methyl-4'-(2-(2-((7-nitrobenzo[c][1,2,5]-oxadiazol-4-yl)amino)ethoxy)ethoxy)-[1,1'-biphenyl]-3-yl)-methoxy)phenyl)...
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
University Of Southern Denmark
Curated by
ChEMBL
Ligand
BDBM50275597
(3-(4-(o-Tolylethynyl)phenyl)propanoic acid | CHEMB...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 68nM
Assay Description:
Agonist activity at human C-terminal eYFP-tagged FFA1 receptor expressed in HEK-293 cells assessed as beta-arrestin2 recruitment incubated for 5 mins...
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
University Of Southern Denmark
Curated by
ChEMBL
Ligand
BDBM50275597
(3-(4-(o-Tolylethynyl)phenyl)propanoic acid | CHEMB...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 45.7nM
Assay Description:
Agonist activity at human FFA1 receptor expressed in human 1321N1 cells assessed as calcium mobilization by fluorescence spectrophotometry
More data for this Ligand-Target Pair
Target Info
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antibodypedia
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Ligand Info
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In Depth
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Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
University Of Southern Denmark
Curated by
ChEMBL
Ligand
BDBM50275597
(3-(4-(o-Tolylethynyl)phenyl)propanoic acid | CHEMB...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 46nM
Assay Description:
Agonist activity at human FFA1 receptor transfected in human 1321N1 cells by calcium mobilization assay
More data for this Ligand-Target Pair
Target Info
PDB
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antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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In Depth
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Article
PubMed
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Target
Free fatty acid receptor 4
(Homo sapiens (Human))
University Of Southern Denmark
Curated by
ChEMBL
Ligand
BDBM50275597
(3-(4-(o-Tolylethynyl)phenyl)propanoic acid | CHEMB...)
Copy SMILES
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Affinity Data
EC50: 2.24E+3nM
Assay Description:
Agonist activity at GPR120 expressed in HEK 293 cells assessed as beta-arrestin recruitment after 5 mins by BRET assay
More data for this Ligand-Target Pair
Target Info
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KEGG
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antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
University Of Southern Denmark
Curated by
ChEMBL
Ligand
BDBM50275597
(3-(4-(o-Tolylethynyl)phenyl)propanoic acid | CHEMB...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 46nM
Assay Description:
Agonist activity at human FFA1 assessed as calcium mobilization measured for 50 intervals of 0.4 secs by microplate reader analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
University Of Southern Denmark
Curated by
ChEMBL
Ligand
BDBM50275597
(3-(4-(o-Tolylethynyl)phenyl)propanoic acid | CHEMB...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 32nM
Assay Description:
Agonist activity at human FFA1 expressed in human 1321N1 cells by calcium fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Free fatty acid receptor 4
(Homo sapiens (Human))
University Of Southern Denmark
Curated by
ChEMBL
Ligand
BDBM50275597
(3-(4-(o-Tolylethynyl)phenyl)propanoic acid | CHEMB...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.45E+3nM
Assay Description:
Agonist activity at C-terminal yellow fluorescent protein-fused human FFA4 receptor transfected in HEK293 cells after 5 mins by BRET assay
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
Copy BDB DOI