Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL

LigandBDBM50239511(CHEMBL4065129)Copy SMILESCopy InChI

Affinity DataIC50:  170nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL

LigandBDBM50239511(CHEMBL4065129)Copy SMILESCopy InChI

Affinity DataIC50:  1.97E+4nMAssay Description:Inhibition of SCD1 in human HepG2 cells assessed as ratio of cellular protein product over substrate after 72 hrsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI