Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50260972(3-(2-aminoquinazolin-6-yl)-4-methyl-1-(4-morpholin...)
Affinity DataIC50:  13nMAssay Description:Inhibition of c-Kit (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50260972(3-(2-aminoquinazolin-6-yl)-4-methyl-1-(4-morpholin...)
Affinity DataIC50:  72nMAssay Description:Inhibition of SCF-induced phosphorylation of c-Kit (unknown origin) in MO7e cells by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50260972(3-(2-aminoquinazolin-6-yl)-4-methyl-1-(4-morpholin...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Src (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50260972(3-(2-aminoquinazolin-6-yl)-4-methyl-1-(4-morpholin...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of Lck (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50260972(3-(2-aminoquinazolin-6-yl)-4-methyl-1-(4-morpholin...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of KDR (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed