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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
4Sc
Curated by
ChEMBL
Ligand
BDBM50328287
(4-(2-hydroxy-3-(1-(5-methylthieno[2,3-d]pyrimidin-...)
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Affinity Data
Ki: 1.39E+3nM
Assay Description:
Displacement of [125I]-cyanopindolol from human adrenergic beta3 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
4Sc
Curated by
ChEMBL
Ligand
BDBM50328287
(4-(2-hydroxy-3-(1-(5-methylthieno[2,3-d]pyrimidin-...)
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Affinity Data
Ki: 2.60E+3nM
Assay Description:
Displacement of [125I]-cyanopindolol from human adrenergic beta2 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
4Sc
Curated by
ChEMBL
Ligand
BDBM50328287
(4-(2-hydroxy-3-(1-(5-methylthieno[2,3-d]pyrimidin-...)
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Affinity Data
Ki: 3.51E+3nM
Assay Description:
Displacement of [125I]-cyanopindolol from human adrenergic beta-1 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
4Sc
Curated by
ChEMBL
Ligand
BDBM50328287
(4-(2-hydroxy-3-(1-(5-methylthieno[2,3-d]pyrimidin-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.50E+3nM
Assay Description:
Antagonist activity at human recombinant adrenergic beta2 receptor expressed in CHO cells assessed as inhibition of isoproterenol-induced cyclic AMP ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
4Sc
Curated by
ChEMBL
Ligand
BDBM50328287
(4-(2-hydroxy-3-(1-(5-methylthieno[2,3-d]pyrimidin-...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 65nM
Assay Description:
Agonist activity at human recombinant adrenergic beta1 receptor expressed in CHO cells assessed as cyclic AMP formation by HTRF assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
4Sc
Curated by
ChEMBL
Ligand
BDBM50328287
(4-(2-hydroxy-3-(1-(5-methylthieno[2,3-d]pyrimidin-...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 20nM
Assay Description:
Displacement of [125I]-cyanopindolol from human adrenergic beta3 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI