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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50549522
(CHEMBL4786038)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate preincubated for 5 mins followed by NADPH generating system addition a...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 2E1
(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50549522
(CHEMBL4786038)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by NADPH generating system addition ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50549522
(CHEMBL4786038)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate preincubated for 5 mins followed by NADPH generating system additi...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50549522
(CHEMBL4786038)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate preincubated for 5 mins followed by NADPH generating system addition...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50549522
(CHEMBL4786038)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate preincubated for 5 mins followed by NADPH generating system addition an...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2A6
(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50549522
(CHEMBL4786038)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by NADPH generating system addition and m...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50549522
(CHEMBL4786038)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate preincubated for 5 mins followed by NADPH generating system addition and...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
P2Y purinoceptor 12
(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50549522
(CHEMBL4786038)
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Affinity Data
IC50: 1.49E+5nM
Assay Description:
Antagonist activity at P2Y12 in human whole blood assessed as suppression of ADP-induced decrease in PGE1-induced VASP phosphorylation measured after...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI