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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
P2X purinoceptor 1
(Mus musculus)
Gwangju Institute Of Science And Technology
Curated by
ChEMBL
Ligand
BDBM50064800
(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
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Affinity Data
IC50: 31nM
Assay Description:
Antagonist activity at mouse recombinant P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current incubated for 2...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
P2X purinoceptor 1
(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50064800
(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 43nM
Assay Description:
Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytes
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 3
(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50064800
(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 74nM
Assay Description:
Inhibition of inward ion current elicited by ATP was determined at recombinant P2X3 receptor expressed in Xenopus oocytes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 3
(Homo sapiens (Human))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50064800
(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
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Copy InChI
Affinity Data
IC50: 84nM
Assay Description:
The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 3 (P2X3 )
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 3
(Homo sapiens (Human))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50064800
(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 96nM
Assay Description:
Antagonist activity at human recombinant P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current incubated for 2...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 3
(Homo sapiens (Human))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50064800
(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 108nM
Assay Description:
Antagonist activity at human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current by two electrode voltage cl...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 2
(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50064800
(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 398nM
Assay Description:
Inhibition of inward ion current elicited by ATP at P2X2 receptor expressed in Xenopus oocytes
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 2
(Homo sapiens (Human))
National Institute Of Diabetes
Curated by
ChEMBL
Ligand
BDBM50064800
(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 400nM
Assay Description:
The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 2 (P2X2) receptor 10 uM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 1
(Meleagris gallopavo)
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50064800
(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
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Affinity Data
IC50: 2.14E+4nM
Assay Description:
Inhibition of 10 nM 2-MeSADP-stimulated phospholipase C in turkey erythrocyte membranes using [3H]-inositol
More data for this Ligand-Target Pair
Target Info
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 1
(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50064800
(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.25E+4nM
Assay Description:
Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X1 receptor expressed in Xenopus oocytes.
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 3
(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50064800
(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.35E+4nM
Assay Description:
Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X3 receptor expressed in Xenopus oocytes.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 1
(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50064800
(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 43nM
Assay Description:
The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI