Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Ingelheim Pharma

LigandPNGBDBM17297(4-[({1-methyl-5-[(2-methyl-1H-1,3-benzodiazol-1-yl...)
Affinity DataKi:  40nM ΔG°:  -43.9kJ/molepH: 8.0 T: 2°CAssay Description:For determination of the inhibition constants (Ki), enzyme inhibition was studied at three different substrate concentrations and seven different con...More data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
Boehringer Ingelheim Pharma

LigandPNGBDBM17297(4-[({1-methyl-5-[(2-methyl-1H-1,3-benzodiazol-1-yl...)
Affinity DataKi:  67nM ΔG°:  -42.6kJ/molepH: 8.0 T: 2°CAssay Description:For determination of the inhibition constants (Ki), enzyme inhibition was studied at three different substrate concentrations and seven different con...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

LigandPNGBDBM17297(4-[({1-methyl-5-[(2-methyl-1H-1,3-benzodiazol-1-yl...)
Affinity DataKi:  780nM ΔG°:  -36.3kJ/molepH: 8.0 T: 2°CAssay Description:For determination of the inhibition constants (Ki), enzyme inhibition was studied at three different substrate concentrations and seven different con...More data for this Ligand-Target Pair
TargetCoagulation factor XI(Homo sapiens (Human))
Boehringer Ingelheim Pharma

LigandPNGBDBM17297(4-[({1-methyl-5-[(2-methyl-1H-1,3-benzodiazol-1-yl...)
Affinity DataKi:  4.10E+3nM ΔG°:  -32.0kJ/molepH: 8.0 T: 2°CAssay Description:For determination of the inhibition constants (Ki), enzyme inhibition was studied at three different substrate concentrations and seven different con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Boehringer Ingelheim Pharma

LigandPNGBDBM17297(4-[({1-methyl-5-[(2-methyl-1H-1,3-benzodiazol-1-yl...)
Affinity DataKi:  9.20E+3nM ΔG°:  -29.9kJ/molepH: 8.0 T: 2°CAssay Description:For determination of the inhibition constants (Ki), enzyme inhibition was studied at three different substrate concentrations and seven different con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Boehringer Ingelheim Pharma

LigandPNGBDBM17297(4-[({1-methyl-5-[(2-methyl-1H-1,3-benzodiazol-1-yl...)
Affinity DataKi:  1.60E+4nM ΔG°:  -28.5kJ/molepH: 8.0 T: 2°CAssay Description:For determination of the inhibition constants (Ki), enzyme inhibition was studied at three different substrate concentrations and seven different con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Boehringer Ingelheim Pharma

LigandPNGBDBM17297(4-[({1-methyl-5-[(2-methyl-1H-1,3-benzodiazol-1-yl...)
Affinity DataKi: >4.00E+4nM ΔG°: >-26.1kJ/molepH: 8.0 T: 2°CAssay Description:For determination of the inhibition constants (Ki), enzyme inhibition was studied at three different substrate concentrations and seven different con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Boehringer Ingelheim Pharma

LigandPNGBDBM17297(4-[({1-methyl-5-[(2-methyl-1H-1,3-benzodiazol-1-yl...)
Affinity DataKi: >5.00E+4nM ΔG°: >-25.5kJ/molepH: 8.0 T: 2°CAssay Description:For determination of the inhibition constants (Ki), enzyme inhibition was studied at three different substrate concentrations and seven different con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed