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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50468638(CHEMBL4288229)
Affinity DataIC50:  2.37E+3nMAssay Description:Inhibition of human NPP3 expressed in COS7 cells using p-nitrophenyl-5'-thymidine monophosphate as substrate preincubated for 5 to 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50468638(CHEMBL4288229)
Affinity DataIC50:  2.53E+3nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells using p-nitrophenyl-5'-thymidine monophosphate as substrate preincubated for 5 to 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50468638(CHEMBL4288229)
Affinity DataIC50:  5.78E+3nMAssay Description:Inhibition of human TNAP expressed in COS7 cells using CDP-star as substrate preincubated for 5 to 10 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50468638(CHEMBL4288229)
Affinity DataIC50:  6.26E+3nMAssay Description:Inhibition of human IAP expressed in COS7 cells using CDP-star as substrate preincubated for 5 to 10 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Rattus norvegicus)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50468638(CHEMBL4288229)
Affinity DataIC50:  5.87E+4nMAssay Description:Inhibition of rat NTPDase1 expressed in CHO cells using ATP as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed