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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
32
hits in this display
Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
Japan Science And Technology Agency
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
IC50: 15.5nM
Assay Description:
Displacement of acetylated histone peptide from BRD4-BD1,2 by FRET assay
More data for this Ligand-Target Pair
Target Info
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
Japan Science And Technology Agency
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
IC50: 15.5nM
Assay Description:
Displacement of tetra-acetylated H4 peptide from human Brd4 bromodomain BD12 after 1 hr by FRET analysis
More data for this Ligand-Target Pair
Target Info
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Target
Bromodomain-containing protein 3
(Homo sapiens (Human))
Japan Science And Technology Agency
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
IC50: 28.4nM
Assay Description:
Displacement of acetylated histone peptide from BRD3-BD1,2 by FRET assay
More data for this Ligand-Target Pair
Target Info
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B.MOAD
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Target
Bromodomain-containing protein 3
(Homo sapiens (Human))
Japan Science And Technology Agency
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
IC50: 28.4nM
Assay Description:
Displacement of tetra-acetylated H4 peptide from human Brd3 bromodomain BD12 after 1 hr by FRET analysis
More data for this Ligand-Target Pair
Target Info
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KEGG
UniProtKB/SwissProt
B.MOAD
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Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
IC50: 29.9nM
Assay Description:
Displacement of tetra-acetylated H4 peptide from human Brd2 bromodomain BD12 after 1 hr by FRET analysis
More data for this Ligand-Target Pair
Target Info
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Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
IC50: 29.9nM
Assay Description:
Displacement of acetylated histone peptide from BRD2-BD1,2 by FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
Japan Science And Technology Agency
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
IC50: 140nM
Assay Description:
Inhibition of His6-tagged BRD4-BD12 expressed in Escherichia coli assessed as inhibition of binding to SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGA-K(Ac)-RHGSGS...
More data for this Ligand-Target Pair
Target Info
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3D Structure (crystal)
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Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
IC50: 160nM
Assay Description:
Inhibition of His6-tagged BRD2 expressed in Escherichia coli assessed as inhibition of binding to SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGA-K(Ac)-RHGSGSK-bio...
More data for this Ligand-Target Pair
Target Info
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Target
Bromodomain-containing protein 3
(Homo sapiens (Human))
Japan Science And Technology Agency
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
IC50: 220nM
Assay Description:
Inhibition of His6-tagged BRD3 expressed in Escherichia coli assessed as inhibition of binding to SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGA-K(Ac)-RHGSGSK-bio...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
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B.MOAD
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Ligand Info
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Copy BDB DOI
Target
Bromodomain-containing protein 3
(Homo sapiens (Human))
Japan Science And Technology Agency
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
IC50: 350nM
Assay Description:
Inhibition of His6-tagged BRD3 expressed in Escherichia coli after 60 mins by fluorescence anisotropy assay
More data for this Ligand-Target Pair
Target Info
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B.MOAD
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
Japan Science And Technology Agency
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
IC50: 470nM
Assay Description:
Inhibition of His6-tagged BRD4 expressed in Escherichia coli after 60 mins by fluorescence anisotropy assay
More data for this Ligand-Target Pair
Target Info
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KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
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PDB
3D Structure (crystal)
Copy BDB DOI
Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
Japan Science And Technology Agency
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
IC50: 501nM
Assay Description:
Binding affinity to His6-tagged BRD4 (unknown origin) after 60 mins by fluorescence anisotropy binding Assay
More data for this Ligand-Target Pair
Target Info
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KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
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CHEMBL
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PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Bromodomain-containing protein 3
(Homo sapiens (Human))
Japan Science And Technology Agency
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
IC50: 631nM
Assay Description:
Binding affinity to His6-tagged BRD3 (unknown origin) after 60 mins by fluorescence anisotropy binding Assay
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PDB
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
IC50: 820nM
Assay Description:
Inhibition of His6-tagged BRD2 expressed in Escherichia coli after 60 mins by fluorescence anisotropy assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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Copy BDB DOI
Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.26E+3nM
Assay Description:
Binding affinity to His6-tagged BRD2 (unknown origin) after 60 mins by fluorescence anisotropy binding Assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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Copy BDB DOI
Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
Kd: 54nM
Assay Description:
Binding affinity to human Brd2 containing bromodomain BD2 expressed in Escherichia coli assessed as dissociation constant at 25 degC by surface plasm...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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CHEMBL
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Copy BDB DOI
Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
Kd: 220nM
Assay Description:
Binding affinity to human Brd2 containing bromodomain BD1 expressed in Escherichia coli assessed as dissociation constant at 25 degC by surface plasm...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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Ligand Info
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CHEMBL
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
Kd: 52nM
Assay Description:
Binding affinity to BRD2-BD1,2 by isothermal titration calorimetry
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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Ligand Info
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CHEMBL
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bromodomain-containing protein 3
(Homo sapiens (Human))
Japan Science And Technology Agency
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
Kd: 46nM
Assay Description:
Binding affinity to BRD3-BD1,2 by isothermal titration calorimetry
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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Article
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Copy BDB DOI
Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
Japan Science And Technology Agency
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
Kd: 52.5nM
Assay Description:
Binding affinity to BRD4-BD1,2 by isothermal titration calorimetry
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
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PDB
3D Structure (crystal)
Copy BDB DOI
Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
Japan Science And Technology Agency
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
Kd: 24nM
Assay Description:
Binding affinity to His6-tagged BRD4 expressed in Escherichia coli by isothermal colorimetric analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
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CHEMBL
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PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Bromodomain-containing protein 3
(Homo sapiens (Human))
Japan Science And Technology Agency
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
Kd: 19nM
Assay Description:
Binding affinity to His6-tagged BRD3 expressed in Escherichia coli by isothermal colorimetric analysis
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
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Ligand Info
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CHEMBL
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Copy BDB DOI
Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
Kd: 52nM
Assay Description:
Binding affinity to His6-tagged BRD2 expressed in Escherichia coli by isothermal colorimetric analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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Ligand Info
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CHEMBL
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In Depth
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PubMed
Copy BDB DOI
Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
Kd: 52nM
Assay Description:
Binding affinity to N-terminal portion of human Brd2 containing bromodomain BD12 expressed in Escherichia coli at 26 degC by isothermal titration cal...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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GoogleScholar
Ligand Info
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Copy BDB DOI
Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
Kd: 52.5nM
Assay Description:
Binding affinity to N-terminal portion of human Brd2 containing bromodomain BD2 expressed in Escherichia coli at 26 degC by isothermal titration calo...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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B.MOAD
GoogleScholar
Ligand Info
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CHEMBL
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In Depth
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Copy BDB DOI
Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
Kd: 46nM
Assay Description:
Binding affinity to N-terminal portion of human Brd2 containing bromodomain BD1 expressed in Escherichia coli at 16 degC by isothermal titration calo...
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Copy BDB DOI
Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
Japan Science And Technology Agency
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
Kd: 19nM
Assay Description:
Binding affinity to N-terminal portion of human Brd4 containing bromodomain BD12 expressed in Escherichia coli by isothermal titration calorimetric a...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
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PDB
3D Structure (crystal)
Copy BDB DOI
Target
Bromodomain-containing protein 3
(Homo sapiens (Human))
Japan Science And Technology Agency
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
Kd: 19nM
Assay Description:
Binding affinity to N-terminal portion of human Brd3 containing bromodomain BD12 expressed in Escherichia coli by isothermal titration calorimetric a...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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Copy BDB DOI
Target
Bromodomain-containing protein 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
Kd: 19nM
Assay Description:
Binding affinity to N-terminal portion of human Brd2 containing bromodomain BD12 expressed in Escherichia coli by isothermal titration calorimetric a...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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Target
ATPase family AAA domain-containing protein 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
Kd: >5.00E+4nM
Assay Description:
Binding affinity to ATAD2 by isothermal titration calorimetric analysis
More data for this Ligand-Target Pair
Target Info
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MMDB
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KEGG
UniProtKB/SwissProt
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
Japan Science And Technology Agency
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
Kd: 19nM
Assay Description:
Binding affinity to BRD4 by isothermal titration calorimetry
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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antibodypedia
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3D Structure (crystal)
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Target
CREB-binding protein
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50365264
(CHEMBL1738926)
Copy SMILES
Copy InChI
Affinity Data
Kd: >5.00E+4nM
Assay Description:
Binding affinity to CREBBP by isothermal titration calorimetric analysis
More data for this Ligand-Target Pair
Target Info
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KEGG
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