Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMyc proto-oncogene protein(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL

LigandBDBM445528(2-[7-(Dimethyl-1H-1,2,3-triazol-5-yl)-6-fluoro-5-[...)Copy SMILESCopy InChI

Affinity DataIC50:  0.600nMAssay Description:Inhibition of c-MYC (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL

LigandBDBM445528(2-[7-(Dimethyl-1H-1,2,3-triazol-5-yl)-6-fluoro-5-[...)Copy SMILESCopy InChI

Affinity DataIC50:  4nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent

LigandBDBM445528(2-[7-(Dimethyl-1H-1,2,3-triazol-5-yl)-6-fluoro-5-[...)Copy SMILESCopy InChI

Affinity DataIC50: <5nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI