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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23548(3-Carboxamide-coumarin deriv., 44 | 8-bromo-6-chlo...)
Affinity DataIC50:  4.40E+3nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23548(3-Carboxamide-coumarin deriv., 44 | 8-bromo-6-chlo...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human factor 12a using S-2302 as substrate assessed as para-nitroaniline release preincubated for 10 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23548(3-Carboxamide-coumarin deriv., 44 | 8-bromo-6-chlo...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23548(3-Carboxamide-coumarin deriv., 44 | 8-bromo-6-chlo...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23548(3-Carboxamide-coumarin deriv., 44 | 8-bromo-6-chlo...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23548(3-Carboxamide-coumarin deriv., 44 | 8-bromo-6-chlo...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed