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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetCytochrome P450 1B1(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50236953(CHEMBL4068333)
Affinity DataIC50:  96nMAssay Description:Binding affinity towards L100I mutant HIV-1 reverse transcriptase (as per ref 10 in the article)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50236953(CHEMBL4068333)
Affinity DataIC50:  624nMAssay Description:Inhibition of human liver CYP1A2 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using CEC as substrate after 10 mins by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50236953(CHEMBL4068333)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro Binding affinity towards 5-hydroxytryptamine 3 receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50236953(CHEMBL4068333)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of human liver CYP2D6 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using EOMCC as substrate after 10 mins by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50236953(CHEMBL4068333)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human liver CYP3A4 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using DBF as substrate after 10 mins by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50236953(CHEMBL4068333)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human liver CYP2C9 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using DBF as substrate after 10 mins by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50236953(CHEMBL4068333)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human liver CYP2C19 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using DBF as substrate after 10 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed