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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Cytochrome P450 3A1
(Rattus norvegicus (rat))
Queen'S University
Ligand
BDBM31672
(imidazole-dioxolane, 24)
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Affinity Data
IC50: 3.40E+3nM
Assay Description:
CYP3A1/3A2-catalyzed erythromycin N-demethylase activity was determined by the spectrophotometric measurement of formaldehyde. Briefly, reaction mixt...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Heme oxygenase 1
(Rattus norvegicus (rat))
Queen'S University
Ligand
BDBM31672
(imidazole-dioxolane, 24)
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Affinity Data
IC50: 3.50E+3nM
pH: 7.4 T: 2°C
Assay Description:
HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Heme oxygenase 2
(Rattus norvegicus (rat))
Queen'S University
Ligand
BDBM31672
(imidazole-dioxolane, 24)
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Affinity Data
IC50: 2.20E+4nM
pH: 7.4
Assay Description:
HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2E1
(Rattus norvegicus (rat))
Queen'S University
Ligand
BDBM31672
(imidazole-dioxolane, 24)
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Affinity Data
IC50: >1.00E+5nM
pH: 7.4
Assay Description:
CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI