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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Acetylcholine receptor subunit beta-like 2
(Drosophila melanogaster)
Gifu University
Curated by
ChEMBL
Ligand
BDBM50251868
((Z)-thiacloprid | CHEMBL451432 | {(2Z)-3-[(6-chlor...)
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Affinity Data
Ki: 1.20nM
Assay Description:
Binding affinity to Drosophila brain nicotinic acetylcholine receptor assessed as [3H]IMI binding by radioligand binding assay
More data for this Ligand-Target Pair
Target Info
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
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Article
PubMed
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Target
Soluble acetylcholine receptor
(Aplysia Californica)
Gifu University
Curated by
ChEMBL
Ligand
BDBM50251868
((Z)-thiacloprid | CHEMBL451432 | {(2Z)-3-[(6-chlor...)
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Affinity Data
Ki: 3.90nM
Assay Description:
Binding affinity to salt water mollusc Aplysia californica AChBP Y55W mutant assessed as [3H]acetamiprid binding by radioligand binding assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
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Article
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PDB
3D Structure (crystal)
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Target
Acetylcholine-binding protein
(Lymnaea stagnalis)
Gifu University
Curated by
ChEMBL
Ligand
BDBM50251868
((Z)-thiacloprid | CHEMBL451432 | {(2Z)-3-[(6-chlor...)
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Affinity Data
Ki: 220nM
Assay Description:
Binding affinity to freshwater snail Lymnaea stagnalis AChBP assessed as [3H]EPI binding by radioligand binding assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
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In Depth
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Article
PubMed
PDB
3D Structure (crystal)
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Target
Neuronal acetylcholine receptor subunit alpha-4
(Gallus gallus)
Gifu University
Curated by
ChEMBL
Ligand
BDBM50251868
((Z)-thiacloprid | CHEMBL451432 | {(2Z)-3-[(6-chlor...)
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Affinity Data
Ki: 240nM
Assay Description:
Binding affinity to recombinant Gallus gallus (chicken) alpha4beta2 nicotinic acetylcholine receptor assessed as [3H]NIC binding by radioligand bindi...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
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KEGG
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PC sid
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In Depth
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Article
PubMed
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Target
Acetylcholine receptor subunit beta-like 2
(Drosophila melanogaster)
Gifu University
Curated by
ChEMBL
Ligand
BDBM50251868
((Z)-thiacloprid | CHEMBL451432 | {(2Z)-3-[(6-chlor...)
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Affinity Data
IC50: 2.70nM
Assay Description:
Inhibition of [3H]IMI binding to Drosophila melanogaster neuronal acetylcholine receptor
More data for this Ligand-Target Pair
Target Info
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholine receptor subunit beta-like 2
(Drosophila melanogaster)
Gifu University
Curated by
ChEMBL
Ligand
BDBM50251868
((Z)-thiacloprid | CHEMBL451432 | {(2Z)-3-[(6-chlor...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.5nM
Assay Description:
Displacement of [3H]IMI from nicotinic acetylcholine receptor in Drosophila melanogaster head membrane after 90 min by filter binding assay
More data for this Ligand-Target Pair
Target Info
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4
(Mus musculus)
University Of California
Curated by
ChEMBL
Ligand
BDBM50251868
((Z)-thiacloprid | CHEMBL451432 | {(2Z)-3-[(6-chlor...)
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Affinity Data
IC50: 860nM
Assay Description:
Inhibition of [3H]nicotine binding to alpha4 nicotinic acetylcholine receptor in Mus musculus (mouse) M10 cells co-expressing beta2 nicotinic acetylc...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
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KEGG
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PC sid
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In Depth
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Article
PubMed
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Target
Neuronal acetylcholine receptor subunit alpha-4
(Gallus gallus)
Gifu University
Curated by
ChEMBL
Ligand
BDBM50251868
((Z)-thiacloprid | CHEMBL451432 | {(2Z)-3-[(6-chlor...)
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Affinity Data
IC50: 860nM
Assay Description:
Displacement of [3H]nicotine from chick alpha4beta2 nAChR
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
University Of California
Curated by
ChEMBL
Ligand
BDBM50251868
((Z)-thiacloprid | CHEMBL451432 | {(2Z)-3-[(6-chlor...)
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Affinity Data
IC50: 1.00E+5nM
Assay Description:
Inhibition of [3H]alpha-BGT binding to alpha7 nicotinic acetylcholine receptor in Homo sapiens (human) SH-SY5Y cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholine receptor subunit alpha
(Homo sapiens (Human))
University Of California
Curated by
ChEMBL
Ligand
BDBM50251868
((Z)-thiacloprid | CHEMBL451432 | {(2Z)-3-[(6-chlor...)
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Affinity Data
IC50: 1.20E+5nM
Assay Description:
Inhibition of [3H]alpha-BGT binding to alpha1 nicotinic acetylcholine receptor in Homo sapiens (human) TE671 cells co-expressing gammaalpha1deltabeta...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
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In Depth
Details
Article
PubMed
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Target
Aldehyde oxidase 1
(Oryctolagus cuniculus)
University Of California
Curated by
ChEMBL
Ligand
BDBM50251868
((Z)-thiacloprid | CHEMBL451432 | {(2Z)-3-[(6-chlor...)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of Oryctolagus cuniculus (rabbit) AOX in liver cytosol
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
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In Depth
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Article
PubMed
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Target
Polyphenol oxidase 2
(Agaricus bisporus (Common mushroom))
University Of California
Curated by
ChEMBL
Ligand
BDBM50251868
((Z)-thiacloprid | CHEMBL451432 | {(2Z)-3-[(6-chlor...)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of Agaricus bisporus (mushroom) tyrosinase
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI