Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50257893(7-(6-chloropyridin-3-yl)-1,7-diazaspiro[4.4]nonane...)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]cytisine from alpha4beta2 nAChR in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50257893(7-(6-chloropyridin-3-yl)-1,7-diazaspiro[4.4]nonane...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human recombinant alpha3beta4 nAChR expressed in human IMR32 cells assessed as calcium dynamics by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50257893(7-(6-chloropyridin-3-yl)-1,7-diazaspiro[4.4]nonane...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human recombinant alpha4beta2 nAChR expressed in human IMR32 cells assessed as calcium dynamics by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed