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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Neuronal acetylcholine receptor subunit alpha-4
(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50257893
(7-(6-chloropyridin-3-yl)-1,7-diazaspiro[4.4]nonane...)
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Affinity Data
Ki: 48nM
Assay Description:
Displacement of [3H]cytisine from alpha4beta2 nAChR in rat brain membrane
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Neuronal acetylcholine receptor subunit alpha-3
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50257893
(7-(6-chloropyridin-3-yl)-1,7-diazaspiro[4.4]nonane...)
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Copy InChI
Affinity Data
EC50: >1.00E+5nM
Assay Description:
Agonist activity at human recombinant alpha3beta4 nAChR expressed in human IMR32 cells assessed as calcium dynamics by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50257893
(7-(6-chloropyridin-3-yl)-1,7-diazaspiro[4.4]nonane...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+5nM
Assay Description:
Agonist activity at human recombinant alpha4beta2 nAChR expressed in human IMR32 cells assessed as calcium dynamics by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI