Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
D(3) dopamine receptor
(Homo sapiens (Human))
Bioprojet-Biotech
Curated by
ChEMBL
Ligand
BDBM50325747
(CHEMBL1223749 | N-(4-(4-(2,3-dichlorophenyl)pipera...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.10nM
Assay Description:
Antagonist activity at D3 receptor (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Université
Curated by
ChEMBL
Ligand
BDBM50325747
(CHEMBL1223749 | N-(4-(4-(2,3-dichlorophenyl)pipera...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.10nM
Assay Description:
Displacement of [3H]spiperone from human dopamine D2S receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H4 receptor
(Homo sapiens (Human))
Bioprojet-Biotech
Curated by
ChEMBL
Ligand
BDBM50325747
(CHEMBL1223749 | N-(4-(4-(2,3-dichlorophenyl)pipera...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.20nM
Assay Description:
Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H4 receptor
(Homo sapiens (Human))
Bioprojet-Biotech
Curated by
ChEMBL
Ligand
BDBM50325747
(CHEMBL1223749 | N-(4-(4-(2,3-dichlorophenyl)pipera...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.20nM
Assay Description:
Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
Bioprojet-Biotech
Curated by
ChEMBL
Ligand
BDBM50325747
(CHEMBL1223749 | N-(4-(4-(2,3-dichlorophenyl)pipera...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 19nM
Assay Description:
Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Bioprojet-Biotech
Curated by
ChEMBL
Ligand
BDBM50325747
(CHEMBL1223749 | N-(4-(4-(2,3-dichlorophenyl)pipera...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 30nM
Assay Description:
Agonist activity at human H4 receptor expressed in CHO cell membranes co-expressing Galphai2 by GTPgamma[35S] binding assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-1A adrenergic receptor
(Homo sapiens (Human))
Université
Curated by
ChEMBL
Ligand
BDBM50325747
(CHEMBL1223749 | N-(4-(4-(2,3-dichlorophenyl)pipera...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 60nM
Assay Description:
Displacement of [3H]prazosin from human adrenergic alpha1A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI