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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCathepsin L(Capra hircus (Goat))
Kurukshetra University

LigandPNGBDBM192652(N’-(2-chlorophenylmethylene)benzohydrazide (1...)
Affinity DataKi:  7.30nM ΔG°:  -48.3kJ/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Capra hircus (Goat))
Kurukshetra University

LigandPNGBDBM192652(N’-(2-chlorophenylmethylene)benzohydrazide (1...)
Affinity DataKi:  210nM ΔG°:  -39.6kJ/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin H(Capra hircus (Goat))
Kurukshetra University

LigandPNGBDBM192652(N’-(2-chlorophenylmethylene)benzohydrazide (1...)
Affinity DataKi:  680nM ΔG°:  -36.6kJ/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed