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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM370901(US10239843, Example 8)
Affinity DataIC50:  1.33E+3nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM370901(US10239843, Example 8)
Affinity DataEC50:  2.30E+3nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM370901(US10239843, Example 8)
Affinity DataEC50:  1.30E+3nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed