Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 12 hits in this display   

TargetHistone deacetylase 6(Homo sapiens (Human))
Purdue Pharmaceutical Products

US Patent
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50:  6nMpH: 8.0Assay Description:Hydroxamic acid is a well know metal-chelating agent, especially for Zn atom. The hydroxamic acid moiety has been demonstrated as the key structural ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Purdue Pharmaceutical Products

US Patent
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50:  9nMpH: 8.0Assay Description:Hydroxamic acid is a well know metal-chelating agent, especially for Zn atom. The hydroxamic acid moiety has been demonstrated as the key structural ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 4(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad

Curated by ChEMBL
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50:  10nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Purdue Pharmaceutical Products

US Patent
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50:  10nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad

Curated by ChEMBL
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50:  10nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad

Curated by ChEMBL
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50:  10nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad

Curated by ChEMBL
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50:  10nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Purdue Pharmaceutical Products

US Patent
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50:  10nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad

Curated by ChEMBL
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50:  17nMpH: 8.0Assay Description:Hydroxamic acid is a well know metal-chelating agent, especially for Zn atom. The hydroxamic acid moiety has been demonstrated as the key structural ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad

Curated by ChEMBL
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50:  25nMpH: 8.0Assay Description:Hydroxamic acid is a well know metal-chelating agent, especially for Zn atom. The hydroxamic acid moiety has been demonstrated as the key structural ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Purdue Pharmaceutical Products

US Patent
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50:  72nMpH: 8.0Assay Description:Hydroxamic acid is a well know metal-chelating agent, especially for Zn atom. The hydroxamic acid moiety has been demonstrated as the key structural ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Purdue Pharmaceutical Products

US Patent
LigandPNGBDBM173621(US9096627, CY190602 )
Affinity DataIC50:  107nMpH: 8.0Assay Description:Hydroxamic acid is a well know metal-chelating agent, especially for Zn atom. The hydroxamic acid moiety has been demonstrated as the key structural ...More data for this Ligand-Target Pair
In DepthDetails US Patent