Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Bromodomain-containing protein 2 [60-463]
(Homo sapiens (Human))
Novartis
US Patent
Ligand
BDBM274268
(5-(5-chloro-1-methyl-6-oxo-1,6-dihydropyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 52nM
pH: 7.5
Assay Description:
All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Bromodomain-containing protein 3
(Homo sapiens (Human))
Novartis
US Patent
Ligand
BDBM274268
(5-(5-chloro-1-methyl-6-oxo-1,6-dihydropyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 95nM
pH: 7.5
Assay Description:
All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Bromodomain-containing protein 4 [44-477]
(Homo sapiens (Human))
Novartis
US Patent
Ligand
BDBM274268
(5-(5-chloro-1-methyl-6-oxo-1,6-dihydropyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 95nM
pH: 7.5
Assay Description:
All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
CREB-binding protein
(Homo sapiens (Human))
Novartis
US Patent
Ligand
BDBM274268
(5-(5-chloro-1-methyl-6-oxo-1,6-dihydropyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 240nM
pH: 7.5 T: 2°C
Assay Description:
All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI