Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCyclin-C(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL

LigandBDBM50189494(CHEMBL3828470)Copy SMILESCopy InChI

Affinity DataIC50:  36nMAssay Description:Competitive binding affinity to full length His-tagged human recombinant CDK8/cyclin C expressed in baculovirus after 20 mins in presence of Alexa647...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCyclin-dependent kinase 8(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL

LigandBDBM50189494(CHEMBL3828470)Copy SMILESCopy InChI

Affinity DataIC50:  70nMAssay Description:Binding affinity to CDK8 (unknown origin) expressed in human 7dF3 cells preincubated for 2 hrs followed by beta-oestradiol addition measured after 24...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI