Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL

LigandBDBM50448678(CHEMBL3127663)Copy SMILESCopy InChI

Affinity DataIC50:  28nMAssay Description:Inhibition of SCD1 in human A431 cells assessed as [13C]-palmitic acid conversion to [13C]-palmitoleic acid after 4 hrs by LC/MS analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Janssen Research And Development

Curated by ChEMBL

LigandBDBM50448678(CHEMBL3127663)Copy SMILESCopy InChI

Affinity DataIC50:  35nMAssay Description:Inhibition of SCD1 in Sprague-Dawley rat liver microsomes using stearoyl-[9,10-3H]-CoA as substrateMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI