Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetHistone deacetylase 2(Homo sapiens (Human))
Taipei Medical University (Tmu)

Curated by ChEMBL

LigandBDBM50241901(CHEMBL4065026)Copy SMILESCopy InChI

Affinity DataIC50:  0.530nMAssay Description:Inhibition of recombinant human full length HDAC2 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University (Tmu)

Curated by ChEMBL

LigandBDBM50241901(CHEMBL4065026)Copy SMILESCopy InChI

Affinity DataIC50:  1.30nMAssay Description:Inhibition of recombinant human full length HDAC1 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University (Tmu)

Curated by ChEMBL

LigandBDBM50241901(CHEMBL4065026)Copy SMILESCopy InChI

Affinity DataIC50:  6.80nMAssay Description:Inhibition of recombinant human full length HDAC6 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetHistone deacetylase 4(Homo sapiens (Human))
Taipei Medical University (Tmu)

Curated by ChEMBL

LigandBDBM50241901(CHEMBL4065026)Copy SMILESCopy InChI

Affinity DataIC50: >100nMAssay Description:Inhibition of recombinant human full length HDAC4 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetHistone deacetylase 8(Homo sapiens (Human))
Taipei Medical University (Tmu)

Curated by ChEMBL

LigandBDBM50241901(CHEMBL4065026)Copy SMILESCopy InChI

Affinity DataIC50: >100nMAssay Description:Inhibition of recombinant human full length HDAC8 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI