Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetHistone acetyltransferase KAT7(Homo sapiens)
Epizyme

US Patent

LigandBDBM606807(US11685732, Compound I-475)Copy SMILESCopy InChI

Affinity DataIC50:  7.50E+4nMAssay Description:Enzyme assay buffer was 50 mM Tris pH 8.0, 0.002% Tween20, 0.005% bovine skin gelatin, and 1 mM dithiothreitol (DTT). For determination of IC50values...More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetHistone acetyltransferase KAT5(Homo sapiens (Human))
Epizyme

US Patent

LigandBDBM606807(US11685732, Compound I-475)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMAssay Description:Enzyme assay buffer was 50 mM Tris pH 8.0, 0.002% Tween20, 0.005% bovine skin gelatin, and 1 mM dithiothreitol (DTT). For determination of IC50values...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Epizyme

US Patent

LigandBDBM606807(US11685732, Compound I-475)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMAssay Description:KAT-6A. Enzyme assay buffer was 50 mM Tris pH 8.0, 0.002% Tween20, 0.005% bovine skin gelatin, and 1 mM dithiothreitol (DTT). For determination of IC...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI