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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetInterleukin-15(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50571050(CHEMBL4851186)
Affinity DataIC50:  710nMAssay Description:Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50571050(CHEMBL4851186)
Affinity DataIC50:  960nMAssay Description:Inhibition of IL2-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-15(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50571050(CHEMBL4851186)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of IL-15 in mouse 32Dbeta cells assessed as decrease in cell growth in presence of RLI incubated for 30 mins followed by RLI addition and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-15(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50571050(CHEMBL4851186)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of IL-15 in mouse 32Dbeta cells assessed as decrease in cell growth in presence of IL2 incubated for 30 mins followed by IL2 addition and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-15(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50571050(CHEMBL4851186)
Affinity DataKd:  5.90E+3nMAssay Description:Binding affinity to recombinant human IL-15 assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed