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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
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Target
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Ligand
BDBM380983
(8-(1-Methyl-4,5-dihydro-1H-indazol- 6-yl)-3,4-dihy...)
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Affinity Data
IC50: 12.9nM
Assay Description:
The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Ligand
BDBM380983
(8-(1-Methyl-4,5-dihydro-1H-indazol- 6-yl)-3,4-dihy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 67nM
Assay Description:
The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI