Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL

LigandBDBM50008151(2-[3-Phenyl-2-(3-pyridin-3-yl-propionylamino)-prop...)Copy SMILESCopy InChI

Affinity DataIC50:  0.230nMAssay Description:The concentration producing 50% inhibition of renin activity in monkey plasma was determined by radioimmunoassay.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCathepsin D(Bos taurus)
Warner-Lambert

Curated by ChEMBL

LigandBDBM50008151(2-[3-Phenyl-2-(3-pyridin-3-yl-propionylamino)-prop...)Copy SMILESCopy InChI

Affinity DataIC50:  1.66E+3nMAssay Description:Inhibitory activity against bovine Cathepsin DMore data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI