Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetProteasome subunit beta type-5(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM50600769(CHEMBL5182823 | US20240043470, Compound 3-14)
Affinity DataIC50:  3.33E+4nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM50600769(CHEMBL5182823 | US20240043470, Compound 3-14)
Affinity DataIC50:  3.33E+4nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM50600769(CHEMBL5182823 | US20240043470, Compound 3-14)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human 20S constitutive proteasome beta-5c subunit using Suc-LLVY-AMC as substrate measured after 1.2 hrs in presence of SDSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM50600769(CHEMBL5182823 | US20240043470, Compound 3-14)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Ac-ANW-AMC as substrate measured after 1.2 hrs in presence of SDSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed