Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Sanofi

US Patent

LigandBDBM50097412(CHEMBL3586448 | US9856257, 37)Copy SMILESCopy InChI

Affinity DataIC50:  20nMAssay Description:For the enzymatic test, human MetAP2 protein was obtained from a culture supernatant of insect cells (sf9) infected with MetAP2 recombinant baculovir...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL

LigandBDBM50097412(CHEMBL3586448 | US9856257, 37)Copy SMILESCopy InChI

Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human METAP2 using Met-Pro-Arg-pNa substrate by para-nitroanilide chromophore release detection assayMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI