Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetProlyl endopeptidase FAP(Mus musculus (Mouse))
Universiteit Antwerp

US Patent
LigandPNGBDBM50434167(CHEMBL2385302 | US9346814, Cmpd No 8 Example 11)
Affinity DataIC50:  12nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl endopeptidase FAP(Mus musculus (Mouse))
Universiteit Antwerp

US Patent
LigandPNGBDBM50434167(CHEMBL2385302 | US9346814, Cmpd No 8 Example 11)
Affinity DataIC50:  12nMAssay Description:Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
University Of Antwerp (Ua)

Curated by ChEMBL
LigandPNGBDBM50434167(CHEMBL2385302 | US9346814, Cmpd No 8 Example 11)
Affinity DataIC50:  710nMAssay Description:Inhibition of human recombinant PREP expressed in Escherichia coli using Z-Gly-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
University Of Antwerp (Ua)

Curated by ChEMBL
LigandPNGBDBM50434167(CHEMBL2385302 | US9346814, Cmpd No 8 Example 11)
Affinity DataIC50:  710nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Universiteit Antwerp

US Patent
LigandPNGBDBM50434167(CHEMBL2385302 | US9346814, Cmpd No 8 Example 11)
Affinity DataIC50: >1.00E+5nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Universiteit Antwerp

US Patent
LigandPNGBDBM50434167(CHEMBL2385302 | US9346814, Cmpd No 8 Example 11)
Affinity DataIC50: >1.00E+5nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Universiteit Antwerp

US Patent
LigandPNGBDBM50434167(CHEMBL2385302 | US9346814, Cmpd No 8 Example 11)
Affinity DataIC50: >1.00E+5nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In DepthDetails US Patent