Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 19 hits in this display
BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
IC50: 6.30nMAssay Description:Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S cells using OPTS as substrate incubated for 40 mins by fluores...More data for this Ligand-Target Pair
BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant nAChRalpha4/beta2 incubated for 120 mins by radiometric scintillation counting methodMore data for this Ligand-Target Pair
BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
IC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate in presence or absence of NADPHMore data for this Ligand-Target Pair
BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)
BDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)