Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Mucosa-associated lymphoid tissue lymphoma translocation protein 1
(Homo sapiens (Human))
Therachem Research Medilab (India)
Curated by
ChEMBL
Ligand
BDBM50169052
(CHEMBL3806235 | US10442808, Example 54 | US9815842...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.00400nM
Assay Description:
Inhibition of MALT1 C domain (329 to 824 residues) (unknown origin) using Ac-Trp-Leu-Arg-Ser-Arg-Cys(PT14)-NH2 as substrate preincubated for 60 mins ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 [329-824]
(Homo sapiens (Human))
Novartis
US Patent
Ligand
BDBM50169052
(CHEMBL3806235 | US10442808, Example 54 | US9815842...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.00400nM
Assay Description:
The assay employs a short peptide substrate labeled with the single fluorophore PT14 as a fluorescence lifetime probe sensitive to the cleavage state...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Mucosa-associated lymphoid tissue lymphoma translocation protein 1
(Homo sapiens (Human))
Therachem Research Medilab (India)
Curated by
ChEMBL
Ligand
BDBM50169052
(CHEMBL3806235 | US10442808, Example 54 | US9815842...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.00400nM
Assay Description:
IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Mucosa-associated lymphoid tissue lymphoma translocation protein 1
(Homo sapiens (Human))
Therachem Research Medilab (India)
Curated by
ChEMBL
Ligand
BDBM50169052
(CHEMBL3806235 | US10442808, Example 54 | US9815842...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.0940nM
Assay Description:
Inhibition of MALT1 (unknown origin) expressed in human Jurkat Clone K22 29Q_H23 cells assessed as IL2 production preincubated for 30 mins followed b...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI