Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL

LigandBDBM50305760(3-(1H-imidazol-1-yl)-6-(4-(2-(trifluoromethyl)phen...)Copy SMILESCopy InChI

Affinity DataIC50:  4nMAssay Description:Inhibition of SCD1 in rat liver microsomesMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 2D6(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL

LigandBDBM50305760(3-(1H-imidazol-1-yl)-6-(4-(2-(trifluoromethyl)phen...)Copy SMILESCopy InChI

Affinity DataIC50:  300nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL

LigandBDBM50305760(3-(1H-imidazol-1-yl)-6-(4-(2-(trifluoromethyl)phen...)Copy SMILESCopy InChI

Affinity DataIC50:  400nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI