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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50247359(CHEMBL4062783)
Affinity DataIC50:  24nMAssay Description:Inhibition of PRMT3 (unknown origin) using C-terminally biotinylated histone H4 as substrate in presence of [3H]S-adenosylmethionine by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50247359(CHEMBL4062783)
Affinity DataIC50:  240nMAssay Description:Inhibition of FLAG-tagged wild type human PRMT3 expressed in HEK293 cells assessed as decrease in exogenous H4R3 dimethylation level using GFP-tagged...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50247359(CHEMBL4062783)
Affinity DataEC50:  2.70E+3nMAssay Description:Binding affinity to beta galactosidase fused human PRMT3 (211 to 531 residues) expressed in human A549 cells after 6 hrs by InCELL hunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50247359(CHEMBL4062783)
Affinity DataEC50:  3.10E+3nMAssay Description:Binding affinity to beta galactosidase fused human PRMT3 (211 to 531 residues) expressed in human HEK293 cells after 6 hrs by InCELL hunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed